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We seek a highly motivated and enthusiastic Researcher for a supportive position at the Institute of Physical Chemistry, Polish Academy of Sciences. The position is part of the project entitled “Breakthrough single cell profiling method for cancer research”, financed by the MNiSW (Ministry of Science and Higher Education). Our laboratory at IPC PAS/ICTER provides an international and interdisciplinary research environment with close links to genomics, single-cell sequencing, molecular biology, biotechnology, and bioinformatics. The project involves profiling of tumor samples using in-house high-throughput single-cell sequencing methods.
Details about the project:
The single-cell sequencing approaches allow researchers to uncover rare cell types, reveal the diversity of cell populations, infer the cellular trajectories, and discover their regulatory mechanisms. Recent progress in developing single-cell techniques has enabled us to study complex biological systems and processes simultaneously at multiple layers of gene regulation. Understanding how the gene expression programs are modulated over time in response of cells during disease progression is one of the long-standing challenges. We aim to develop new approaches to comprehensively interrogate the dynamics of gene regulatory elements, and downstream gene expression programs, using state-of-the-art chemical, biophysical, and genomic tools.

About the group: The Computational Genomics Group at IPC PAS led by dr. Marcin Tabaka leverages experimental and computational approaches in high-throughput single-cell transcriptome and epigenome profiling to address fundamental questions in biomedical research (https://tabaka-lab.org).

● Cell culturing;
● Design, perform, analyze and interpret experiments, including profiling of single cells from human tumor samples;

● Library preparation for NGS;
● Quality control assessment of next-generation sequencing data generated in the project;
● Optimization of single-cell sequencing protocols;

● Analyses of data and manuscript writing.

• We offer a laboratory technician position (full-time employment) at the Institute of Physical Chemistry PAS with a gross salary of around 4950 PLN gross per month financed from the MNiSW “Nauka dla Społeczeństwa II”, project No NDS-II/SP/0195/2023/01. The offer is for 6 months with a possible extension.
• Engagement into an ambitious research program and opportunity to build an academic career.

• Social benefits (including co-financing of MULTISPORT card, co-financing of cultural/ sport/ touristic activities of employees, etc.).

The job in the exciting interdisciplinary project.
The successful candidate will be able to take advantage of all programs in the IPC PAS, including Young Scientists of IPC PAS competition and Mobility of Young Scientists of IPC PAS competition.
The Institute provides an opportunity to participate in ERASMUS+ program.

● Solid knowledge and familiarity with laboratory techniques in molecular and cell biology;
● 1-4 years of research experience;
● MSc degree in molecular biology, biotechnology or biochemistry is a plus;
● Good command of English

The Commission will take into account the following criteria and evaluate applications on a point scale:
● Competence for specific tasks in a research project
● Previous achievements
● References