Living Materials

Research group no. 2

Living Materials

Group leader

dr hab. Jan Paczesny, prof. instytutu

Research topics

The main idea, which unifies the research of the group, is to create a connection between biology and material chemistry. Such a connection can be accomplished in at least two ways: 1) by using natural building blocks, perfected by evolution (biomolecules, viruses, whole organisms) to prepare functional materials or 2) applying knowledge of physical chemistry, material engineering and nanotechnology to create modern nanomaterials that can be used in biology and medicine.

Members

  • dr inż. Konrad Giżyński
  • mgr Mateusz Wdowiak
  • mgr inż. Rafał Zbonikowski
  • Enkhlin Ochirbat
  • dr inż.    Witold    Adamkiewicz
  • dr Prabhjot Singh
  • dr Hossein Maleki Ghaleh
  • mgr Bartosz Kamiński
  • mgr inż. Enkhlin Ochirbat
  • mgr Gunjan Tiwari
  • mgr Mateusz Wdowiak
  • mgr inż. Rafał Zbonikowski

Research

Combining precise measurements (physical chemistry) and applying them to biochemistry and molecular biology problems might result in a major improvement of understanding of important scientific issues, which are not available for only chemists, only physicist nor only biologists. The variety and functionality of biological materials is almost impossible to be mimicked in artificial systems. Therefore, utilization of sensitivity and diversity of biomolecules and primitive organisms might result in spectacular properties of novel bio-materials. Moreover, biomolecules are usually monodisperse, even despite high molecular mass. Therefore, equations and laws established for pure systems are applicable also for bio-systems. One of the aims of the research is to learn how to take the best parts from biology, biochemistry, physical chemistry and nanotechnology and combine them together. This might be done by incorporation of biocomponents into nanotechnology or by utilization of nanotechnology and materials chemistry in the services of biology and medicine. We aim to combine both approaches and build a true “bridge” – a two way connection between the fields.

Publications

2021

Wdowiak, M., Ochirbat, E., & Paczesny, J.
Gold—Polyoxoborates Nanocomposite Prohibits Adsorption of Bacteriophages on Inner Surfaces of Polypropylene Labware and Protects Samples from Bacterial and Yeast Infections.
Viruses, https://doi.org/10.3390/V13071206

Paczesny, J.
The use of probes and bacteriophages for bacteria detection.
In V. Gurtler (Ed.), Fluorescent Probes (1st ed.). Academic Press. https://www.elsevier.com/books/fluorescent-probes/gurtler/978-0-12-823515-7

Richter, Ł., Księżarczyk, K., Paszkowska, K., Janczuk-Richter, M., Niedziółka-Jönsson, J., Gapiński, J., Łoś, M., Hołyst, R., & Paczesny, J.
Adsorption of bacteriophages on polypropylene labware affects the reproducibility of phage research.
Scientific Reports, https://doi.org/10.1038/s41598-021-86571-x

Paczesny, J., Wolska-Pietkiewicz, M., Binkiewicz, I., & Janczuk-Richter, M.
Langmuir and Langmuir Blodgett films of zinc oxide (ZnO) nanocrystals coated with polyhedral oligomeric silsesquioxanes (POSS).
Journal of Colloid and Interface Science, https://doi.org/10.1016/j.jcis.2021.05.08

Kuczynska, K., Bończak, B., Rárová, L., Kvasnicová, M., Strnad, M., Pakulski, Z., Cmoch, P., & Fiałkowski, M.
Synthesis and cytotoxic activity of 1,2,3-triazoles derived from 2,3-seco-dihydrobetulin via a click chemistry approach.
Journal of Molecular Structure,  https://doi.org/10.1016/J.MOLSTRUC.2021.131751

Richter, Ł., Paszkowska, K., Cendrowska, U., Olgiati, F., Silva, P., Gasbarri, M., Guven, P., Paczesny, J., & Stellacci, F.
Broad-spectrum nanoparticles against bacteriophage infections.
Nanoscale, https://doi.org/10.1039/D1NR04936D

Gizynski, K., Makuch, K., Paczesny, J., Zhang, Y., Maciołek, A., & Holyst, R.
Internal energy in compressible Poiseuille flow.
Physical Review E,  https://doi.org/10.1103/PhysRevE.104.055107

2022

Auksorius, E., Borycki, D., Wegrzyn, P., Žičkienė, I., Adomavičius, K., Sikorski, B. L., & Wojtkowski, M.
Multimode fiber as a tool to reduce cross talk in Fourier-domain full-field optical coherence tomography.
Optics Letters, https://doi.org/10.1364/OL.449498

Bończak, B. B., & Fiałkowski, M.
Donor–Acceptor Stenhouse Adducts for Stimuli-Responsive Self-Assembly of Gold Nanoparticles into Semiconducting Thin Films.
The Journal of Physical Chemistry C,  https://doi.org/10.1021/ACS.JPCC.2C00084

Paczesny, J., Wdowiak, M., & Ochirbat, E.
Bacteriophage-Based Biosensors: Detection of Bacteria and Beyond.
Nanotechnology for Infectious Diseases,  https://doi.org/10.1007/978-981-16-9190-4_20

2023

Zbonikowski, Rafal; Iwan, Michalina; Paczesny, Jan

Stimuli-Responsive Langmuir Films Composed of Nanoparticles Decorated with Poly(N-isopropyl acrylamide) (PNIPAM) at the Air/Water Interface

ACS OMEGA 2023  8, 26

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Zbonikowski, Rafal; Mente, Pumza; Bonczak, Bartlomiej; Paczesny, Jan

Adaptive 2D and Pseudo-2D Systems: Molecular, Polymeric, and Colloidal Building Blocks for Tailored Complexity

NANOMATERIALS 2023  13, 5, 855

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Wdowiak, Mateusz; Mierzejewski, Patryk A.; Zbonikowski, Rafal; Bonczak, Bartlomiej; Paczesny, Jan

Congo red protects bacteriophages against UV irradiation and allows for the simultaneous use of phages and UV for membrane sterilization

ENVIRONMENTAL SCIENCE-WATER RESEARCH & TECHNOLOGY 2023  9, 3, 696-706

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“Makuch, Karol, Holyst, Robert, Gizynski, Konrad,  Maciolek, Anna, Zuk, Pawel J"

Steady-state thermodynamics of a system with heat and mass flow coupling     

JOURNAL OF CHEMICAL PHYSICS 2023  159 (19), 194113

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Raza, Sada; Grotek, Mateusz; Adamkiewicz, Witold; Nikiforow, Kostiantyn; Mente, Pumza; Paczesny, Jan

Enhancing the antimicrobial activity of silver nanoparticles against ESKAPE bacteria and emerging fungal pathogens by using tea extracts

NANOSCALE ADVANCES 2023  5, 21, 5786-5798

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Lyczek, Jan; Bonczak, Bartlomiej; Krzyminska, Izabela; Gizynski, Konrad; Paczesny, Jan

Gold-oxoborate nanocomposite-coated orthodontic brackets gain antibacterial properties while remaining safe for eukaryotic cells

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS  2023 111, 5, 996-1004

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Chavan, Rohit D.; Bonczak, Bartlomiej; Kruszynska, Joanna; Mahapatra, Apurba; Ans, Muhammad; Nawrocki, Jan; Nikiforow, Kostiantyn; Yadav, Pankaj; Paczesny, Jan; Sadegh, Faranak; Unal, Muhittin; Akin, Seckin; Prochowicz, Daniel

Molecular Engineering of Azahomofullerene-based Electron Transporting Materials for Efficient and Stable Perovskite Solar Cells

CHEMISTRY OF MATERIALS  2023 35, 19, 8309-8320

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O'Connor, Ryan; Matsoso, Joyce B.; Mashindi, Victor; Mente, Pumza; Macheli, Lebohang; Moreno, Beatriz D.; Doyle, Bryan P.; Coville, Neil J.; Barrett, Dean H.

Catalyst Design: Counter Anion Effect on Ni Nanocatalysts Anchored on Hollow Carbon Sphere

NANOMATERIALS 2023 13, 3, 426

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Holyst, Robert; Makuch, Karol; Gizynski, Konrad; Maciolek, Anna; Zuk, Pawel J.

Fundamental Relation for Gas of Interacting Particles in a Heat Flow

ENTROPY 2023  25, 9, 1295

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Holyst, Robert; Zuk, Pawel J.; Makuch, Karol; Maciolek, Anna; Gizynski, Konrad

Fundamental Relation for the Ideal Gas in the Gravitational Field and Heat Flow

ENTROPY 2023 25, 11, 1483

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Celikkin, Nehar; Presutti, Dario; Maiullari, Fabio; Volpi, Marina; Promovych, Yurii; Gizynski, Konrad; Dolinska, Joanna; Wisniewska, Agnieszka; Opallo, Marcin; Paradiso, Alessia; Rinoldi, Chiara; Fuoco, Claudia; Swieszkowski, Wojciech; Bearzi, Claudia; Rizzi, Roberto; Gargioli, Cesare; Costantini, Marco

Combining rotary wet-spinning biofabrication and electro-mechanical stimulation for the in vitro production of functional myo-substitutes

BIOFABRICATION  2023  15, 4, 45012

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Maciolek, Anna; Holyst, Robert; Makuch, Karol; Gizynski, Konrad; Zuk, Pawel J.; Martyushev, Leonid M.

Parameters of State in the Global Thermodynamics of Binary Ideal Gas Mixtures in a Stationary Heat Flow          

ENTROPY 2023 25, 11, -1505

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Atamas, N. O.; Yablochkova, K. S.; Gavryushenko, D. A.; Lazarenko, M. M.

Structure and Dynamic Inhomogeneity of Liquids on the Liquid-Gas Coexistence Curve Near the Triple Point

JOURNAL OF PHASE EQUILIBRIA AND DIFFUSION  2023 44, 6, 704-713

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Ochirbat, Enkhlin; Zbonikowski, Rafal; Sulicka, Anna; Bonczak, Bartlomiej; Bonarowska, Magdalena; Los, Marcin; Malinowska, Elzbieta; Holyst, Robert; Paczesny, Jan

Heteroaggregation of virions and microplastics reduces the number of active bacteriophages in aqueous environments               

JOURNAL OF ENVIRONMENTAL QUALITY 2023 52, 3, 665-677

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Sada Raza, Mateusz Wdowiak, Jan Paczesny

An Overview of Diverse Strategies To Inactivate Enterobacteriaceae-Targeting Bacteriophages

EcoSal Plus 2023 11, 1

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N. O. Atamas, K. S. Yablochkova, M. M. Lazarenko  G. Taranyik         

Relaxation, temporal diffusion, and polarity of aromatic hydrocarbons in ionic liquid

APPLIED NANOSCIENCE 2023 13, 5101–5113

Financing

National Science Centre, grant

SONATA 15 UMO-2019/35/D/ST5/03613 (kierownik dr K. Giżyński) 2020 - 2023

OPUS 18 UMO-2019/35/B/ST5/03229 (kierownik dr J. Paczesny) 2020 - 2023

SONATA BIS UMO-2017/26/E/ST4/00041 (kierownik dr J. Paczesny) 2018 - 2022